rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
PNPLA3 rs738409 is associated with renal glomerular and tubular injury in NAFLD patients with persistently normal ALT levels.
|
31519069 |
2020 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In the U.S. population, PNPLA3 I148M and higher NAFLD liver fat and fibrosis scores were associated with increased liver disease mortality.
|
31705824 |
2020 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The TM6SF2 E167K variant was associated with NAFLD in northeast China, and there was an interaction between the PNPLA3 I148M and TMS6F2 E167K variants in NAFLD.
|
31054977 |
2020 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This study aimed to elucidate whether PNPLA3 I148M is involved in NF-kB-related inflammation regulation in NAFLD.
|
31793207 |
2020 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Patients with NAFLD carrying PNPLA3 rs738409 G>C variant are at higher risk of liver-related events and death.
|
31419571 |
2020 |
rs58542926
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The TM6SF2 E167K variant was associated with NAFLD in northeast China, and there was an interaction between the PNPLA3 I148M and TMS6F2 E167K variants in NAFLD.
|
31054977 |
2020 |
rs58542926
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs58542926 polymorphism in TM6SF2 (transmembrane 6 superfamily member 2) is a genetic factor predisposing to nonalcoholic fatty liver disease.
|
31356578 |
2020 |
rs266729
|
|
|
0.040 |
GeneticVariation |
BEFREE |
ADIPOQ G rs266729 and TNF- 308 A allele are associated with obesity, MetS/NAFLD and insulin resistance.
|
31659105 |
2020 |
rs17618244
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, we showed an association between the rs17618244 KLB variant, which leads to reduced KLB expression, and the severity of NAFLD in pediatric patients.
|
31655133 |
2020 |
rs537635771
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to elucidate whether PNPLA3 I148M is involved in NF-kB-related inflammation regulation in NAFLD.
|
31793207 |
2020 |
rs768007422
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to elucidate whether PNPLA3 I148M is involved in NF-kB-related inflammation regulation in NAFLD.
|
31793207 |
2020 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
PNPLA3-I148M: a problem of plenty in non-alcoholic fatty liver disease.
|
31062641 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The PNPLA3 loss-of-function variant p.I148M is a strong genetic determinant of nonalcoholic fatty liver disease.
|
31454802 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Emerging evidence also suggests a potential association between patatin-like phospholipase domain-containing protein-3 (PNPLA3) rs738409 genotype (the most important genetic variant associated with NAFLD) and decreasing kidney function, independent of NAFLD.
|
31738141 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The objective of the study is to explore the impact of PNPLA3 I148M polymorphism on eGFR in children with obesity with and without NAFLD.
|
31184438 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Polymorphisms 455 T > C of APOC3 and rs738409 C > G of PNPLA3 were associated with NAFLD.
|
31216264 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs7</span>38409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD).
|
31851849 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
PNPLA3 variant rs738409 has been identified as important progression factor in patients with ALD and NAFLD, the most common liver diseases worldwide.
|
30362098 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
NAFLD association of PNPLA3 rs738409 was more pronounced among lean individuals (one-tailed p < 0.05) compared to the whole cohort sample.
|
30539516 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
PNPLA3 rs738409 polymorphism is not only a factor significantly associated with the susceptibility of NAFLD, but also related to the susceptibility of aggressive diseases.
|
30762732 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In a sample of 230 overweight/obese children, 105 with NAFLD (hepatic fat fraction ≥5% by magnetic resonance imaging) and 125 without NAFLD, rs738409 in PNPLA3, rs58542926 in TM6SF2, rs1260326 in GCKR, and rs641738 in MBOAT7 were genotyped.
|
31505904 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The rs738409 C>G variant of the patatin-like phospholipase domain containing 3 gene (PNPLA3) increases the risk of non-alcoholic fatty liver disease (NAFLD) with no predisposition for insulin resistance.
|
30673802 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
PNPLA3 I148M is associated with increased risk of prediabetes, metabolic syndrome and insulin resistance in obese patients with NAFLD.
|
31826069 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M (rs738409) genotype influences clinical/biochemical characteristics in patients with nonalcoholic fatty liver disease (NAFLD), but whether PNPLA3-I148M (rs738409) genotype also influences the diagnostic performance of noninvasive diagnostic tests for NAFLD is uncertain.
|
31677195 |
2019 |
rs738409
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Relationship Between PNPLA3 rs738409 Polymorphism and Decreased Kidney Function in Children With NAFLD.
|
30912854 |
2019 |